The Design and Fabrication of Platform Device for Dna Amplification

Thermalcycler were extensively used machine for amplify DNA sample. One of the major problems in the working time was that it spent most of time for cooling and heating. In order to improve the efficient, this study presented a novel method for amplify DNA sample. For this concept, the DNA sample in the silicon chamber which was pushed by a beam through three temperature regions around a center and then the DNA segments could be amplified rapidly after 30 cycles. The polymerase chain reaction platform was composed of thin-film heaters, copper plates, DC powers, and temperature controllers. The photolithography and bulk etching technologies were utilized to construct the thin-film heater and DNA reaction chambers. Finally, 1 pound gL 100bp DNA segment of E. coli K12 was amplified successfully within 36 minutes on this PCR platform.Comment: Submitted on behalf of TIMA Editions (http://irevues.inist.fr/tima-editions

Organic light-emitting diodes based on a cohost electron transporting composite

The efficiency of green organic electroluminescent devices have been improved by cohosting the electron dominant complex, 4,7-diphenyl-1,10- phenanthroline into the traditional electron transporting layer of tris (8-hydroxyquinoline) aluminum. In this cohost strategy, we demonstrate that the luminous efficiency is enhanced by >20% while the driving voltage can be reduced by ∼30% in a uniformly mixed composition as compared to the traditional device configuration. The corresponding device lifetime under atmospheric condition is extended by a factor of ∼1.8, attributed to the reduction of the accumulated positive charges near the electron-hole recombination regime. Results indicate that the knowledge of bulk conductivity engineering of organic n-type transporters is essential in enhancing organic light-emitting devices. © 2006 American Institute of Physics.published_or_final_versio

Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice

Cyclophosphamide (CY) is a cytostatic agent that produces systemic toxicity especially on cells with high proliferative capacity, while polysaccharides from Angelica sinensis (AP) have been shown to increase the turnover of gastrointestinal mucosal and hemopoietic stem cells. It is not known whether AP has an effect on CY-induced cytotoxicity on bone marrow and gastrointestinal tract. In this study, we assessed the protective actions of AP on CY-induced leukopenia and proliferative arrest in the gastroduodenal mucosa in mice. Subcutaneous injection of CY (200 mg/kg) provoked dramatic decrease in white blood cell (WBC) count and number of blood vessels and proliferating cells in both the gastric and duodenal mucosae. Subcutaneous injection of AP significantly promoted the recovery from leukopenia and increased number of blood vessels and proliferating cells in both the gastric and duodenal tissues. Western blotting revealed that CY significantly down-regulated the protein expression of vascular endothelial growth factor (VEGF), c-Myc and ornithine decarboxylase (ODC) in gastric mucosae but had no effect on epidermal growth factor (EGF) expression. AP also reversed the dampening effect of CY on VEGF expression in the gastric mucosa. These data suggest that AP is a cytoprotective agent which can protect against the cytotoxicity of CY on hematopoietic and gastrointestinal tissues when the polysaccharide is co-administered with CY in cancer patients during treatment regimen.published_or_final_versio

Rapid-eye-movement-sleep (REM) associated enhancement of working memory performance after a daytime nap

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The role of religion in moderating the impact of life events on material life goals: Some evidence in support of terror management theory.

How would religion and a life event carrying an existential threat (LEET) jointly impact a person's life goals of becoming wealthy and successful in one's career? Goal reprioritisation, socioemotional selectivity, and gerotranscendence theories predict a shift away from material goals following a LEET, independent of the effect of religion. However, terror management theory (TMT) predicts that the effect of death thoughts depends on one's prevailing cultural values. As religion can be regarded as a culture, it is possible that Christians' and non-believers' material life goals would be differentially altered by LEET. Data from 1259 young Chinese adults reveal no main effect of LEET, but a strong effect of religion. Moreover, there was an interaction effect between LEET and religion on material life goals: LEET weakened material goals for Christians but not for non-believers. These findings suggest that TMT is more suitable than the other theories for predicting life goal changes.postprin

Implicit person theories and change in teacher evaluation: A longitudinal field study

Adopting a longitudinal field study, this paper investigates whether entity theorists (students who believe human attributes are fixed) are less likely than incremental theorists (students who believe human attributes are malleable) to change their evaluations of a teacher in accordance with his behavioral changes. An instructor exhibited some forgetful behaviors in the first half of a course, and ceased doing so in the second half. Consistent with our hypothesis, incremental theorists adjusted their perceptions of the instructor. They rated him as less forgetful accordingly at the end of the course than at the middle. Entity theorists, however, did not show this change. With improved ecological validity, this study extends previous laboratory studies to teacher evaluation. © 2010 Copyright the Authors. Journal compilation © 2010 Wiley Periodicals, Inc.postprin

A study on the effect of COX-2 inhibitors on gastric mucosal prostaglandin synthesis

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A study of resiliency among Chinese health care workers: Capacity to cope with workplace stress

This paper reports a study of resiliency to cope with workplace stress among Chinese health care workers. We adopted a qualitative-quantitative-biomarker approach to conduct interviews, focus group discussions, and a two-wave longitudinal survey. Wave 1 survey was conducted among health care workers in Hong Kong and Mainland China (N = 773). Amongst them, 287 took part in Wave 2 survey. A confirmatory factor analysis consistently supported a 9-item scale. A sub-sample's (N = 33) resiliency was positively related to salivary IgA levels (an immune marker). Results from hierarchical regressions demonstrated that resiliency measured in Wave 1 was positively related to job satisfaction, work-life balance, and quality of life; and negatively related to physical/psychological symptoms and injuries at work in Wave 2. © 2009 Elsevier Inc. All rights reserved.postprin

"Faith Maturity Scale" for Chinese: A Revision and Construct Validation

Using a large sample of Chinese Christians (n = 2,196), we examined the internal structure, reliability, and validity of the Faith Maturity Scale (FMS). Despite its being developed in North America, and for a mainline Protestant population, the FMS was shown to have validity among non-Western, non-mainline Protestants. There is convergent validity with self-reported religious practices and a belief measure of religiosity. Our analyses also confirmed good construct validity with the Big Five personality dimensions, social axioms, attributional style, and quality of life. FMS remained associated with religious practices and high quality of life after personality was statistically controlled. Findings supported that the Chinese version of the FMS assesses the same theoretical construct as does the original scale and that the distinction between the vertical and horizontal dimensions of faith maturity is meaningful. © 2011 Copyright Taylor and Francis Group, LLC.postprin